Women who have had a family member diagnosed with ovarian cancer often have a genetic predisposition to ovarian cancer, and women with this genetic predispose can be more likely to have multiple family members diagnosed with the disease.
The National Cancer Institute estimates that approximately 2 million Americans have the genetic mutation called ovarian hyperplasia, and approximately 200,000 women are diagnosed with this mutation each year.
According to the American Society for Reproductive Medicine, the risk for ovarian cancer is one in 1,000, and about 30 percent of women with the mutation will develop ovarian cancer in their lifetime.
Patients with this rare genetic mutation have higher rates of ovarian and cervical cancer, which may be associated with other medical conditions such as cardiovascular disease, type 2 diabetes, or certain cancers of the uterus and vagina.
Some women with ova cancer may also develop an abnormal uterine cervix, which can lead to an infection and increase the risk of ectopic pregnancy.
According to a 2016 study, one in three women with ovarian hyperplastic syndrome will have a second diagnosis of ovarian or cervical cancer.
And, the odds are that if they do, they’ll live a very long time.
About 1 in 20 women with cancer will die from their cancers in their lifetimes, and there are more than 400,000 deaths each year from ovarian cancer worldwide, according to the World Health Organization.
Obesity is also a risk factor for ovarian cancers.
A recent study published in the journal Diabetes, Obesity and Metabolism found that women with overweight were twice as likely to develop ovarian tumors as women with normal weight.
Obese women also have a higher risk of developing ovarian cancer compared to women of normal weight, and the women who are obese have a lower risk of having ovarian cancer than those with normal body weight.
For more information about the genetics of ovarian tumors, please visit the American Cancer Society’s website.